04
2023
-
08
Based on the R&D and mass production capabilities of raw materials, products fill the global gap
Classification:
【概要描述】Lixin Science combines these three requirements and forms a uniformly dispersed composite material that can absorb artificial bone through super dispersion technology, forming a rubber like shape that can be shaped freely with surgical tools, resulting in a full filling effect. For comminuted fractures, the patient's fragmented bone can be integrated into it to optimize the osteogenic effect. Secondly, it has strong resistance to liquid phase disintegration. It can be soaked in water at 37 ° C for one month without disintegration and can be stably applied in various surgical environments. Based on the above, this product can save surgical time in practical applications. Thirdly, the product has gradient degradation characteristics, which can provide a favorable microenvironment for bone regeneration and achieve rapid bone conduction regeneration. In addition, in view of the slow bone healing caused by diabetes, the latest research of Lixin Science shows that its product has obvious osteogenic effect in the skull defect of diabetes rats. This undoubtedly brings more possibilities to the products of Lixin Science. In order to achieve many possibilities, Lixin Science has recently launched an A+round of financing. In combination with the development plan of promoting product certification and listing as soon as possible in the short term, the financing amount will be used for product research and development, team building, and market promotion. When talking about the company's longer-term strategic goals, Sun Yang told us the origin of the company's name, which comes from Zhang Zai, a famous figure from the Northern Song Dynasty, who said, "For heaven and earth, for the people.". "As a medical enterprise, this is the beacon of the spirit of science." He explained, "The corporate culture of science is consistent with the profound meaning expressed by this ancient saying. We hope to use modern science and technology to truly benefit patients. Let the enterprise develop independently, do well in expanding and strengthening, and become the brand of the country's nation. This is the ideal we have always adhered to."
Raw materials are the cornerstone of products. Lixin Science relies on an excellent R&D team and excels in raw material research and mass production.
Sun Yang described his team as "complementary advantages, fine division of labor, and the combination of theory and practice." As a member of the core team of Lixin Science, he has deeply cultivated polymer material research and development, material processing technology, medical device animal clinical trials, and accumulated years of industry experience. Overall, the team focuses on research and development, with highly educated talents from domestic and foreign universities and industry professionals with rich professional experience working together in both theoretical and practical aspects of product development, forming a three-dimensional talent pool.
Taking the preparation of L-polylactic acid (PLLA) as an example, it is highly sensitive to moisture, unstable in performance, easy to decompose, and difficult to produce with high purity and high yield. The Lixin Scientific Research Team has developed patented technologies such as "continuous heating cracking", "efficient solvent purification", and "ultra-high vacuum anhydrous anaerobic synthesis" to overcome process difficulties, achieving controllable synthesis and industrial application of two-level raw materials for medical grade polylactic acid family materials.
Among them, "two levels" refer to monomers and polymers. According to Sun Yang, Lixin Science has 4-5 types at the monomer level. By combining these monomers in different proportions and orders, as well as designing different molecular weights and structures, an endless variety of polymer raw materials can be synthesized. This is equivalent to the formation of a polylactic acid family material library by Lixin Science, with huge customization space for the research and development of absorbable implants that can meet different needs.
At present, Lixin Science has over 80 patents, including more than 20 invention patents, and has formed intellectual property rights related to core composite materials; And a 2-ton production capacity factory with customized production equipment and production line transformation.
Sun Yang stated that based on the design capabilities of raw materials, on the one hand, Lixin Science can closely follow clinical needs to form its own industrial chain closed loop. Starting from raw materials according to clinical needs, customization and transformation are carried out, and innovative processes are used to form their own innovative products for clinical use, which are then continuously upgraded through clinical feedback. On the other hand, customized raw materials can be supplied to other medical device manufacturers.
From raw materials to products, Lixin Science's high-performance terminal products can meet the clinical needs of absorbable induction regeneration.
Taking bone fillers as an example, there are various types of bone defects in clinical practice, which requires bone fillers to have malleable properties; At the same time, it also needs to have anti liquid phase collapse performance, which can resist the erosion of blood and water without collapse. In addition, the new generation of bone fillers requires biodegradable absorption and induction of bone regeneration.
The mainstream products of bone fillers worldwide can be divided into four categories. In terms of performance, there is still a blank space for high-performance bone filler products that can be molded, resistant to liquid phase disintegration, and highly efficient bone induction regeneration.
Lixin Science combines these three requirements and forms a uniformly dispersed composite material that can absorb artificial bone through super dispersion technology, forming a rubber like shape that can be shaped freely with surgical tools, resulting in a full filling effect. For comminuted fractures, the patient's fragmented bone can be integrated into it to optimize the osteogenic effect.
Secondly, it has strong resistance to liquid phase disintegration. It can be soaked in water at 37 ° C for one month without disintegration and can be stably applied in various surgical environments. Based on the above, this product can save surgical time in practical applications.
Thirdly, the product has gradient degradation characteristics, which can provide a favorable microenvironment for bone regeneration and achieve rapid bone conduction regeneration. In addition, in view of the slow bone healing caused by diabetes, the latest research of Lixin Science shows that its product has obvious osteogenic effect in the skull defect of diabetes rats. This undoubtedly brings more possibilities to the products of Lixin Science.
In order to achieve many possibilities, Lixin Science has recently launched an A+round of financing. In combination with the development plan of promoting product certification and listing as soon as possible in the short term, the financing amount will be used for product research and development, team building, and market promotion.
When talking about the company's longer-term strategic goals, Sun Yang told us the origin of the company's name, which comes from Zhang Zai, a famous figure from the Northern Song Dynasty, who said, "For heaven and earth, for the people.".
"As a medical enterprise, this is the beacon of the spirit of science." He explained, "The corporate culture of science is consistent with the profound meaning expressed by this ancient saying. We hope to use modern science and technology to truly benefit patients. Let the enterprise develop independently, do well in expanding and strengthening, and become the brand of the country's nation. This is the ideal we have always adhered to."